Download Center
To set up and run Xenium Ranger, please follow the following steps:
Xenium Ranger 4.0.0 (Sep 2, 2025)
- Self-contained, relocatable tar file. Does not require centralized installation.
- Contains binaries pre-compiled for CentOS 7 and later/RedHat 7.4 or Ubuntu 16.04 and later.
- Runs on Linux systems that meets the minimum compute requirements.
tar.gz compression
Download for Linux 64-bit (tar.gz)File size: 3.5 GBmd5sum: c063db33f59ac7df642ca6b8d3ae6adccurlwgetcurl -o xeniumranger-4.0.0.tar.gz "https://cf.10xgenomics.com/releases/xeniumranger/xeniumranger-4.0.0.tar.gz?Expires=1774647566&Key-Pair-Id=APKAI7S6A5RYOXBWRPDA&Signature=LvyjtJEzBVyTmEUd9NXs-SX2mAb1JuPw9Ff4L3zW5uy~qStx5ZpsMc3iqrG2zUeKSev~e0RyP2bmOB3Bnv2kpmAu7iouyUNo6HRm2qGHScriWQVg1L6rzECbWJuxS2f2g2qTnKh1VGV~8lsntC8sDBr2qFMu-3zVk625o7bOQ9e8KpUkT73GwmB9QYjqXr3OcYqDykw9B8Hiw9kYLz0J0divpiL8P25nvGafiuc~G6ANuLumniX6JErOb6mkO68SZKgqUwLWKm0JG7AdbJ72fOpH9amCQY-rhl3shXQmJe6aqr-Sa4B7VdXLGL-Xpn~eJ5ibt-Pxqk1VyYRdd5xb2g__"tar.xz compression
Download for Linux 64-bit (tar.xz)File size: 2.3 GBmd5sum: 3a1636bd176257c0edad991660b13bfdcurlwgetcurl -o xeniumranger-4.0.0.tar.xz "https://cf.10xgenomics.com/releases/xeniumranger/xeniumranger-4.0.0.tar.xz?Expires=1774647566&Key-Pair-Id=APKAI7S6A5RYOXBWRPDA&Signature=nX0uOavBn82nyikNyLHLTRqc-tRqk~MO-uIU9GHKL9ATOjozS7vzRiZxtVDoXYkIF9LG730evf6oPQ80OG3gfuj8IisuVsxGfFE-Ii5lP5FRtmc7PFRsYWEaBorD-Y~j5aP7vthxipGQLD7~2dsoN1UeNU9CaeZXNzC04nLGHHruVnR74hR7RWcMs67hg0hKEssQIvBOOFdPe9vW1B8I9Wj~wWjUVfucw2WeNLHWeswZhNA7jjHOaUa1SFPntcLZ586o3z3BzKissEcbsArf1eS2mUvq0I~--S7mO5LkBNCb3JohP8L49zLly~LuDMJNL1u-GdIBaIHjre-uRdHFSA__"
Download is unavailable on mobile devices.
Xenium Ranger 4.0.0 highlights
- Supports reanalysis of Xenium Onboard Analysis data up to XOA v4.0.
- Segment previously un-segmentable large cells with the new large cell segmentation feature.
- Substitute a boundary or interior stain with a Xenium Protein image for multimodal cell segmentation.
- Map cell IDs between a Xenium Ranger output and the imported segmentation to join metadata for a third-party analysis.
- And more - see full release notes.
System requirements
System requirements
View the minimum requirements to run Xenium Ranger pipelines
Installation
Xenium Ranger Installation
View instructions on how to install Xenium Ranger