Download Center
To set up and run Xenium Ranger, please follow the following steps:
Xenium Ranger 4.0.0 (Sep 2, 2025)
- Self-contained, relocatable tar file. Does not require centralized installation.
- Contains binaries pre-compiled for CentOS 7 and later/RedHat 7.4 or Ubuntu 16.04 and later.
- Runs on Linux systems that meets the minimum compute requirements.
tar.gz compression
Download for Linux 64-bit (tar.gz)File size: 3.5 GBmd5sum: c063db33f59ac7df642ca6b8d3ae6adccurlwgetcurl -o xeniumranger-4.0.0.tar.gz "https://cf.10xgenomics.com/releases/xeniumranger/xeniumranger-4.0.0.tar.gz?Expires=1770475106&Key-Pair-Id=APKAI7S6A5RYOXBWRPDA&Signature=Qe7Ytv2n8tuTrxAYaGD7j-USbki5xOhG6DLT5FJ26baCvehPIIFVHJA23gZsv-LiC4rEtB0wRlgHOli6fi3oJ3nw8sg~htndDhFk4Qihmbloa1fQgwzORDcUttGZxGd2E04LffqdSjiLmP2R3HoTt~Fdrn878HKv-Mk--FJHn0tLBy6YVEUrRg7DXNy0cdkzwJKmkgFHWmx~Ibv62xMvbFdXaWiiC7x2AmYEw1kIGIGp9Ec9PQFuss8GvUlIpx5Qfr4yxJI78hzsmwkdJ~LR-58hhWSfI~FgD3xrIh8pL3PAnjKmpgnUfI2McZSxkI8fvdWh-VvuTSO2hSsD78JubQ__"tar.xz compression
Download for Linux 64-bit (tar.xz)File size: 2.3 GBmd5sum: 3a1636bd176257c0edad991660b13bfdcurlwgetcurl -o xeniumranger-4.0.0.tar.xz "https://cf.10xgenomics.com/releases/xeniumranger/xeniumranger-4.0.0.tar.xz?Expires=1770475106&Key-Pair-Id=APKAI7S6A5RYOXBWRPDA&Signature=gCPUPYOM73qdUQ-nWnzkgl0pTqITPuEpA0WFzWa~F0ottxjAcl1YVEA8jetj0bKERp73GETdweqQYVOCEv7Pd3PsX3z5JiMzYXhwslNdFC~E-~m3Ie-Dgf3zZeRq6Aq36XBGt8QuOXXygF04LsRpbWxeSEX2RsfdAaHKScgAiUe6ujdSnvt91d9CcDnvDFrs~R4uiUko2Hz2mdpsfd0yBmwJxZisMTrfY986mt4D6VQDIM6tvOGeqQmGVPcLtncgA-yu2PSMrMQvTYqlX0ophPu~aFGeTHW1ym6KGAN6CP4Byx8Y9WI1IUdlA7JoLsWc7eQmLTVvJPc2aBrzGlb9Xw__"
Download is unavailable on mobile devices.
Xenium Ranger 4.0.0 highlights
- Supports reanalysis of Xenium Onboard Analysis data up to XOA v4.0.
- Segment previously un-segmentable large cells with the new large cell segmentation feature.
- Substitute a boundary or interior stain with a Xenium Protein image for multimodal cell segmentation.
- Map cell IDs between a Xenium Ranger output and the imported segmentation to join metadata for a third-party analysis.
- And more - see full release notes.
System requirements
System requirements
View the minimum requirements to run Xenium Ranger pipelines
Installation
Xenium Ranger Installation
View instructions on how to install Xenium Ranger