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Previous Versions

Previous Versions

Space Ranger 4.0.1 (Jun 12, 2025)

  • tar.gz compression

    Download for Linux 64-bit (tar.gz)
    File size: 885 MB
    md5sum: b0beb100947717cee8c7ad0d7a9f0247
    curl -o spaceranger-4.0.1.tar.gz "https://cf.10xgenomics.com/releases/spatial-exp/spaceranger-4.0.1.tar.gz?Expires=1770480758&Key-Pair-Id=APKAI7S6A5RYOXBWRPDA&Signature=jaHYildmvelj0zmLhWuaEiNLJhcT1tfff6XSP8NeqkZ6xYRJ-UkmYiskiAqyl1JF3v0boomm2CN-4WzUYThQOcxyDNvGaeFjc9TcJTD2~QDUjfoQ55gpL0XyTPBxPtuAJKPiFdep5F1DE2KmeXXfU~gqUXmv0E8yM1-7vaudDbCLKnSIVKh459WtLgDU-o4bDlGdyq~hZ2n9jrvq8iTfiAzclw3rwms24fHBQHO0NdnR7GJxiNSGog6dFxI5NqzLnOiV9eVdgPeQvVgFW0KyaG9g2fQ4qtALslZTSqtB9YYJHJwAS1LwuS8Gpwij70kNUxprbDF5ySQW-9aRTil4DQ__"
  • tar.xz compression

    Download for Linux 64-bit (tar.xz)
    File size: 582 MB
    md5sum: 3610ff948a6f8129cf49509f1bb34970
    curl -o spaceranger-4.0.1.tar.xz "https://cf.10xgenomics.com/releases/spatial-exp/spaceranger-4.0.1.tar.xz?Expires=1770480758&Key-Pair-Id=APKAI7S6A5RYOXBWRPDA&Signature=Cdzhrnqps~fRWOpRf-oJKfGbGbqm8o~U7eZ3SkNgJdP9HaRvozL1BcMsivNbc3yUZV1kNGziKXdUUEl4ejfBCJKgpCuuRpeL1WsKGWZ8u2q-XbD9ZzqCUg99mOOIhX8tgfDmY1H--cKq94RBLFmnEMd~L36cpM~hoY~rMlDvwRFbLOa5o5V9ESBNE5LiKiuatrVvdEolNh6S~cdVHpRvznQLDelnjIu1pGy07Q8Aa8lBVhMZnu0cJtsSa6GfkKnJDaAVydcjHiolekRaN-VOmEsy~o1fTzutNbqWHDFDrnDGnIgD77D5nbcxlGdXgF1g6PWAruXMiD7bb4d3aEPHAg__"

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Space Ranger v4.0.1 highlights

  • Space Ranger v4.0 now supports Visium HD 3' Gene Expression!
  • Cell and nucleus segmentation are now included for Visium HD and Visium HD 3' data with H&E images.
  • Space Ranger v4.0 now features a new UMI-based registration algorithm for Visium HD and Visium HD 3' data.
  • Starting with v4.0, anonymized telemetry data is collected and sent to 10x Genomics.
Release notes

Space Ranger 3.1.3 (Feb 6, 2025)

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    Download for Linux 64-bit (tar.gz)
    File size: 829 MB
    md5sum: 2cc7128cd538108d2a8a737ec54df484
    curl -o spaceranger-3.1.3.tar.gz "https://cf.10xgenomics.com/releases/spatial-exp/spaceranger-3.1.3.tar.gz?Expires=1770480758&Key-Pair-Id=APKAI7S6A5RYOXBWRPDA&Signature=l0O~Ggx3fKP~Vq-2D-OSC2BdJmRO3vV64oFcJ45TiF9L4UNODakW39GXeu9VEcKr4R9TF6EQGIDORzGxms9Uvrn9J0zqm1PEcuqbbxXRhMRkdbO8Tqjv~vZp6ERtBGX-4eXOFFYHBwZxK7yomhszGCfJOXRx8owqoQr-6Rhq4bkeGmTS~tfxlVUS6~73nXGlmWf64~LJnPeRRdhSOGlUqlrIv07kYjkuJS6PtLjia-uhIqtAS5x3C9rWeez7SXi4cDria2AsPa0OdhBPSXyGsumuNar1vVPDyyMrwmpF2dt7hDDgepsrUTAmiXzJQ-~-6FtxcZjQLxbCRUxvS2wk5g__"
  • tar.xz compression

    Download for Linux 64-bit (tar.xz)
    File size: 529 MB
    md5sum: 2756aa7e3b66139059667117546c41bb
    curl -o spaceranger-3.1.3.tar.xz "https://cf.10xgenomics.com/releases/spatial-exp/spaceranger-3.1.3.tar.xz?Expires=1770480758&Key-Pair-Id=APKAI7S6A5RYOXBWRPDA&Signature=cVjxKi7VvWFhRwpg51Jabu1dLmyMnd1lTh6A5AzkKWUKOL6-Dc3b0Jx7TC8Uo1jrwiyHxXk2AHKeUZv5FDetRr4NkjjRRIpUFVTEgzX6ure0h0E7ZLyVXvqD13Ms1O032omkVqVqnY9AxYfHbLU40cAlWTaf6JVscg9TTkk03P87sgjFQLmiSyAxM4Nc34V0llpbhmRcxvY22TsWojrcXDZ-AEd0HUrIFmobKnXlN6vYivNt3aNh5Ry6PYV4fmKKcHwEF3lg6IELNMfdwHuYefiIUIKZ9Jf-~AuncKY2wpwUHX7kI9a6OquWsawjd~Q884pc4X~Bo~p0i-w9MkLFwg__"

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Space Ranger v3.1.3 highlights

  • Restored support for AVX1 machines.
  • Other miscellaneous bug fixes.

Space Ranger 3.1.2 (Nov 18, 2024)

  • tar.gz compression

    Download for Linux 64-bit (tar.gz)
    File size: 867 MB
    md5sum: 949088b1e2cc5bd03079b60a65b41d39
    curl -o spaceranger-3.1.2.tar.gz "https://cf.10xgenomics.com/releases/spatial-exp/spaceranger-3.1.2.tar.gz?Expires=1770480758&Key-Pair-Id=APKAI7S6A5RYOXBWRPDA&Signature=MMT0NefheZEe82D53rWwKYHowVTlR-3pzMcoPOq5nCuE9nS~~KPlcI5vQoJHuTt~JmOGbKEKRtIeB14-cFYv6Pe4GEY~Znlh8fbRzvAn6r9tjQ2b3qxeXLluMxvhKRVh87NrXz~K5ZaNosJsJoDeANGJ1jaVAbxIGTtvK-3rek1yBi6O2e~ROTATujN9ylA7Gn4Lei-dSXBGdS~hOdCJfC3kS0i8S69MQSyQcSscu9T~YB00LAezirp5vEcWrHQHmyrj92dS~3dT-clt3o3fAscsjIjLh5jDpwej80KGgZ~2X2fqFpJw-Kso8ZG~k3eURYqmpTag~3w94B9enPorFQ__"
  • tar.xz compression

    Download for Linux 64-bit (tar.xz)
    File size: 552 MB
    md5sum: 5a923ae250eea2974fd1cef7b2f9c1e2
    curl -o spaceranger-3.1.2.tar.xz "https://cf.10xgenomics.com/releases/spatial-exp/spaceranger-3.1.2.tar.xz?Expires=1770480758&Key-Pair-Id=APKAI7S6A5RYOXBWRPDA&Signature=Xx6XkowStbLjITYCUlupArWwChNs3R2x4BakICUqPZGRSK5HdqgbFnlHgREsXPZk2UgtZImevAAHNM~EzBUtEfDa-deBK6tbEmAEDo~gi6dyJSBvfAgkzrpEK0LIhCJUZ1rEw4s9-NQRixpVob1jrfP37GQ0T7PcvrKz3c4XoezGoCvEaS17OEBoa~lbM6wnvEt6AjYrQKDf95doXbe1qgSgthOAaclmwJtyBoC6yT7oOaTwP9sa2W0m54sbN2COlJM1-f8PSllW-D~dL~V25h3EC3Ry9yNCHx9qpuEn1jq0XgVYIO3T2-4XlY3EUz9uZ3k1e6~0aMAMSNUQkwTS2Q__"

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Space Ranger v3.1.2 highlights

  • In Space Ranger v3.1.2, the pipeline automatically corrects Visium HD CytAssist images generated with instrument firmware v2.1 to account for a bug that affects registration between gene expression data and the microscope image.
  • Adds metrics “Number of UMIs per mm squared of Tissue” and “Number of Reads per mm squared of Tissue” to the web_summary.html file.

Space Ranger 3.1.0 (Aug 28, 2024)

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    Download for Linux 64-bit (tar.gz)
    File size: 827 MB
    md5sum: 13a2c82adfb1f1efb737e2be121000d1
    curl -o spaceranger-3.1.0.tar.gz "https://cf.10xgenomics.com/releases/spatial-exp/spaceranger-3.1.0.tar.gz?Expires=1770480758&Key-Pair-Id=APKAI7S6A5RYOXBWRPDA&Signature=I6rILVmhNHXU5~waua~C8yuXpKk1GFsB40ULoi1nXSSA~WtcCD9U-vGVuCvjO3Tk0H9mPPKYeP0owq-Y~pyeox432eWtcGHuIZVoQJtN1XoxByEBr4P0o3u32xSrto~G2xq9VCPobg7pUzygZ5NdJ5rqbhErtGv3hUFX4pGFL1oXO--R4~gPi462fRe87jGoEG1cfVOqLAVz1e2gOhpL4SsgTfts9i1pfhnDlcBLeAlm4gmUhgnOBONMU62RPChkM2lu8tt5LPgzUFo4xd-q~~rPxmtg3hGFuhciQdRNETGQB14GrfJ8nBuLXNPiXOTV6-indgE2apusZGcAtBCJTQ__"
  • tar.xz compression

    Download for Linux 64-bit (tar.xz)
    File size: 527 MB
    md5sum: 28010d3724e9effc488470a961fe39fd
    curl -o spaceranger-3.1.0.tar.xz "https://cf.10xgenomics.com/releases/spatial-exp/spaceranger-3.1.0.tar.xz?Expires=1770480758&Key-Pair-Id=APKAI7S6A5RYOXBWRPDA&Signature=BP5P-6TMTrHK6x98cZfPmYfIJ8y8EJQeysnZPX5FFGBYqvFoC2D8xo0~MmreviQn74ZLcWN0I1da3oqwjj3Pjo1aojaXjol5dfITdiEoZd2h-X1~EfTGI7Gqcu7w9rOxzNowG-WMSp4NWo7y41UACehFXn4C7GrzBpswLoYDoSlv6ZNiQ8QhOCijYC60DelPbX0q0apwpZ5FHTsNm61XiQoOUUXrhah3kDf0QYssL8OZyvlFGJlBjWhBUhFFW37mfnUFylqlddIJDipWZluLWYN2HvZUWEpjUtj7rxIygOX4uHcfGSr~CJ29yJLEgjiM5EYCuHuoUFstSqb2Cd1MXA__"

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Space Ranger 3.1.0 highlights

  • In Space Ranger v3.1.0, the pipeline has been overhauled to significantly improve the CytAssist to microscope image registration process.

Space Ranger 3.0.1 (May 31, 2024)

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    Download for Linux 64-bit (tar.gz)
    File size: 757 MB
    md5sum: ae65e7ffdddbb966277b7d1776f8c63c
    curl -o spaceranger-3.0.1.tar.gz "https://cf.10xgenomics.com/releases/spatial-exp/spaceranger-3.0.1.tar.gz?Expires=1770480758&Key-Pair-Id=APKAI7S6A5RYOXBWRPDA&Signature=eFNCMQk8Jv~BsM1PRMdoKPgCSceYKql9gvVVcsTnSuZ8MwzKy~gYqtJupSPVV4qFGX7Zrus-WX~Jf~8Yavz0JwDnHJ-WSy6WrVHrBndlmlUFEULuZLgJnVGVkStiEMl~IK240hCw1laWIjobnN7avPXJN-NOP98ESVbvJrDiBIS3ZtV8sqMOHwUoUo9T9y5AnNltZ~cxronYLwW9CETp9b-lWGw0kdNW5amctGLjsrvnI6qUl3lsykjmPX4J8jAfh0kRRftGnzGmVciu96IEo1RwcwzCFN0AqrPp2RTfAPsij-aY~z1V4OT0NPbnMqQ8BJPrZl9r4snQ~GeJKhMI-w__"
  • tar.xz compression

    Download for Linux 64-bit (tar.xz)
    File size: 481 MB
    md5sum: 451495ee2074ff9adbac49ff8851ea1b
    curl -o spaceranger-3.0.1.tar.xz "https://cf.10xgenomics.com/releases/spatial-exp/spaceranger-3.0.1.tar.xz?Expires=1770480758&Key-Pair-Id=APKAI7S6A5RYOXBWRPDA&Signature=NU698RcDI77XUc7l~heGB0QIYe5F0aeHPB~mQxFUtdssFlqVVF~jY7YEahLhqNWK5rU35XhjC0VWdHNy7~GwhagRkFn~64k973LJ1wME-C6-0xX3RT9GXoQAwVNCU-6lSCaOXtE~my0NzJVak~jY37Dfrw-Oo-UWReZTwPnYk93mFm3PcGK-Hw4zg-ycZ2LcrA7upgyp87N0zbXLHYnY-cWgpSQgshwQdKNrrPnzkOuO0rn5aOeM1DDWmE815O~nXLXK52K7lMnfrHzHNjmDWvVnlBCVckUrAu-XGwjmx8U2Tf8U2LHtBlc7i2p0WqH4KT-qBZ-CgmGbJ6VuLmRagA__"

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Space Ranger 3.0.1 highlights

  • Space Ranger v3.0 now supports Visium HD!
  • Space Ranger v3.0.1 includes bug fixes and other improvements.

Space Ranger 3.0.0 (Mar 25, 2024)

  • tar.gz compression

    Download for Linux 64-bit (tar.gz)
    File size: 795 MB
    md5sum: 19f4443f10cf94aff5768bd8968cb214
    curl -o spaceranger-3.0.0.tar.gz "https://cf.10xgenomics.com/releases/spatial-exp/spaceranger-3.0.0.tar.gz?Expires=1770480758&Key-Pair-Id=APKAI7S6A5RYOXBWRPDA&Signature=iv7T5Qg4HJQ83eBcTmfINHidXWATllWmYwCN1hGmlsq6~2nTWBScMho3BUXHpedMJw3Yg-JEdyEu-TInfVISIcoezj63-f~1-6nyXWr5fnX6jKATvEE8VgVstkVeQf9K0tfh~O62aNK0zqTaH9SD67wo7cvUv1Hp4aapooEtvpdkR3MQ3N8TDpQixeLO4wKSCvuIo3RzFZA4jYZBpfUjQaZ00WPAoS4-zdw77MCwfR-sBj4Od1RWPbDf10ejKlfsb0hu6ae-au2LGzci~unyFxNtYMRxg-16L8OSmIUu2TpCUkBXyQZym95vO1VhDLgN0gHQ3TDpoLuAUBVagIRuhg__"
  • tar.xz compression

    Download for Linux 64-bit (tar.xz)
    File size: 507 MB
    md5sum: cd02b83fe849672066c40a1734819432
    curl -o spaceranger-3.0.0.tar.xz "https://cf.10xgenomics.com/releases/spatial-exp/spaceranger-3.0.0.tar.xz?Expires=1770480758&Key-Pair-Id=APKAI7S6A5RYOXBWRPDA&Signature=nGXaEUMeV1vyADicBw6W1QiVLamchXgJSJqI40pHC3VdhWUp3imNEbS32OXc7fvO3yidkJpHaEnlQc22RueAkhNAhl3446LwdCPfun788MnfIAFgCtCVm2J~0Fg5czw6uOiO9XUXPjtaxfPsiSn9ERYguAaTpAiS2iR8E3KiDdSYWuHSt2su9ncq7rGoHb0DxKJZIzSOIoaAp9q4IYexNq~mXZq76VoXQPbakr6PWJhVys9A2fqkD0hBhRIxYa8pASWoK7LPD7hUt~LyTJR~h74FI-3GMCaWf-2AZGSIWa-VCNGEgrf6Bm6~XeCKMLN0xQrD7Na1UrH28yD18kCCtQ__"

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Space Ranger 3.0.0 highlights

  • Space Ranger now supports Visium HD!

Space Ranger 2.1.1 (Oct 2, 2023)

  • tar.gz compression

    Download for Linux 64-bit (tar.gz)
    File size: 707 MB
    md5sum: 0ef64524af2735bd2a0fc9eef5a605f6
    curl -o spaceranger-2.1.1.tar.gz "https://cf.10xgenomics.com/releases/spatial-exp/spaceranger-2.1.1.tar.gz?Expires=1770480758&Key-Pair-Id=APKAI7S6A5RYOXBWRPDA&Signature=U0J9nSKG4Tm~5clf6RHKLy5g3B7q1TDcRFSQlOwKbmyCIY2wOzdMx3lsWlZTrhWd~wD09GAjWRz0IZ5hSw9Rww-VVOw5RRu9DJmhdoUtK0RV75i30JnsH4BWZXor8ZzAa3s46H47jVxMUeeo7M9Z2V0Y2skw9HshNJ7a2nI8sNai51pXNrVnq6yixwICi3gXQ8M9wCf76BGa4ajter9sNSCywok5nNyT-1Vsr9vYZFCA3UpbwwJUVn3NNyj7OwssKgHWDdm7uMUy~fO1H7iLfnBqT8ty7nTgWma43kSK8nRtbdHbXzU6r3cdpZCevjZBgFhsOFK5g0kQa1WQMN2WQQ__"
  • tar.xz compression

    Download for Linux 64-bit (tar.xz)
    File size: 465 MB
    md5sum: e1204bb11b3589bc5d5af244b51bfc18
    curl -o spaceranger-2.1.1.tar.xz "https://cf.10xgenomics.com/releases/spatial-exp/spaceranger-2.1.1.tar.xz?Expires=1770480758&Key-Pair-Id=APKAI7S6A5RYOXBWRPDA&Signature=g~PnDWXQaQ4Q1XSY2jK1WbItwha454PU9P0tIOfpBHdaoL6Zug1lt90jNaEIEryYQ-NfAyvpR8279D-DGWyqzA5tIPHZfXTr9v9twhb2PuS5EDcOBzOC1DRemGp6RquFcGF2xaQ1KcpoV5bXlHfRxqlmOcRxbvk0uzT2ZcdbL8SSRu20KnDcU0l9rzq5ZVE3N9sTKyZblBL0e-nKWUB4uUTvVrJp5DdmdR7wsuc2E4pAnPRZ9OUT-pEMM3z8H16TuroyhVx3F76mXZ0fc5uWo45jx~IjhVGU6PT2lNQVaFF0gri4sAwoTuGZIJ1UUlxLqOYaYcFPHm~VR5S1ovVTYg__"

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Space Ranger 2.1.1 highlights

  • Fixed a bug where 8-bit grayscale images were inadvertently turned into 8-bit RGB color images for tissue registration.

Space Ranger 2.1.0 (May 16, 2023)

  • tar.gz compression

    Download for Linux 64-bit (tar.gz)
    File size: 707 MB
    md5sum: ee94c453c44770b2b69d6be46b948e3e
    curl -o spaceranger-2.1.0.tar.gz "https://cf.10xgenomics.com/releases/spatial-exp/spaceranger-2.1.0.tar.gz?Expires=1770480758&Key-Pair-Id=APKAI7S6A5RYOXBWRPDA&Signature=f~8eNGTGGdLH90j9nC57GS3OboBIoGndNd6iRHMZn8nX5ia-zaEnIt-V~SBCvxZUxZJxq331-8zObWxdnYcChb0WtXGWHk-1BvmJZEv2Op-j0OFgpr5jKWFU9cC-z~JxrlRyzIW~4h0YkvV4hXT5LV44noRssTMMA~fgfok0SZoM5wDW2oBI1OmpdMOwJ0Szr1ZTgJFRhGX4sjj480je5OXkX8AGWeg~4gXS1gXNWDC9zGgWWWsHbzWBCukAXykOOYei1F-PK97QnUUSPdp3x80eAGzhQkP2aY7XcXSS5vIyDaDyGsiObBMO7D3Uzu4NGaTsZlcLfiCR~tnjfDzP9Q__"
  • tar.xz compression

    Download for Linux 64-bit (tar.xz)
    File size: 465 MB
    md5sum: a0d90129a81c41cbdd728e23a4d25161
    curl -o spaceranger-2.1.0.tar.xz "https://cf.10xgenomics.com/releases/spatial-exp/spaceranger-2.1.0.tar.xz?Expires=1770480758&Key-Pair-Id=APKAI7S6A5RYOXBWRPDA&Signature=H2TpVIyJWGpFLRtrLkrMPpeXJ0Xm6dSIrUYT8GHOIlUhkL60kp2cBW6gVkbNtsQ-7Vacjrp-b57CmPIHk0GzU30IqSTPuxm~w40EHAcs2M9De1YYRr34VjqvZDzd~7z0IiBa6ICE6Ur3L3QdPB-6aBrETFq~gYD075BhTaVO88f1ihAdYVrd8BO22dspvzvr5f7VITfsaZEewCEJ80tAqe3oRYKoSUXLHOuRPMMlvyzDHhmhtCzmW5SM4avG9HdGEai~m3UylvfmDckzprDrP37Ouo0ZR4IrgSWqk695gK8qVqMBvvVBcmsjsCm4Db2-~BygVfKy5l24IYpiKKxZBQ__"

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Space Ranger 2.1.0 highlights

  • New feature: Gene + Protein Expression on Visium CytAssist.
  • New feature: Reference-free spot deconvolution.
  • Added support for bigtiff (btf, tf2, and tf8) image file extensions.

Space Ranger 2.0.1 (Dec 7, 2022)

  • tar.gz compression

    Download for Linux 64-bit (tar.gz)
    File size: 664 MB
    md5sum: 26151804338ae4d4b44151232bd64b50
    curl -o spaceranger-2.0.1.tar.gz "https://cf.10xgenomics.com/releases/spatial-exp/spaceranger-2.0.1.tar.gz?Expires=1770480758&Key-Pair-Id=APKAI7S6A5RYOXBWRPDA&Signature=g3ZPrjP3J~kXtqICVAx8nF3O2-JYWXI38MDKvAiQoen6NGd-O4aRB8ObZS4YO2MKo-VWURobZzItrnF2qXcDrFMBt-Aw0eK3IxiwyKavad3RqQHIKTJjMGpYZUtcIQmXJNyUnaJIIqPgOXt9-ko9Fyh2FKuLMJqtQVlykj4R8szAb8L5ozdh1xsdpe5TxZz6zK9A7GCkxSwOVxF7kWjG092nympkze1yR7wXKtGWV-PriC1qiiUOMmq-dLLOy2~Xiwg5G1yRwYdaMaTmZEQTcactg-mu3t~GXYLFrHGb-SIFITJgP7N6bf1SINz5JW8vGcy-EVsFBx9thZfMV2nMUA__"

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Space Ranger 2.0.1 highlights

  • Reclustering workflow now supports generating a UMAP projection in addition to the t-SNE projection.
  • Visium Image Manual Aligner now includes additional support for images with difficult to detect fiducials.
  • A new Spatial Enrichment table which allows users to sort and filter features by their Moran’s I value for Visium Spatial Gene Expression is added.

Space Ranger 2.0.0 (Jul 18, 2022)

  • tar.gz compression

    Download for Linux 64-bit (tar.gz)
    File size: 662 MB
    md5sum: aec9ec128c7bc9fbf9fd6d31aa390d4c
    curl -o spaceranger-2.0.0.tar.gz "https://cf.10xgenomics.com/releases/spatial-exp/spaceranger-2.0.0.tar.gz?Expires=1770480758&Key-Pair-Id=APKAI7S6A5RYOXBWRPDA&Signature=DXH-F62PRAlzkEc~fOyxZta5jXjf-eJFDLv3KQLAH7n0r3gMBAuNKZ7Ylqvi87muQFgPwpQ60mFpslmsustOhwBdnh~hyAJNtmd9uUuEw9QeeTehHKyv7ONfFpJkNvUi4hDNoIYn2u~2kzxFYg9z7G81srgUU6jAYX~emnkbzTjOAZFwMBd5gaSHlVcXPhCy8EtlmO0FoD82uQQj0OrQdDM0IKRORNkLuqAFmbGyHxtTe~r51Xv6ia2Ytv78BIoffPmpJMxYdeyRUObU3AdG2Dw759GmQQZC6t4GOq6r7mOJpQOk8fUUedaSLYgqhcclz4foc-n3TZ3FicLbJriG0w__"

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Space Ranger 2.0.0 highlights

  • Space Ranger now supports CytAssist-enabled Gene Expression analysis and includes image registration between the CytAssist image and the microscope image of the same tissue section.
  • spaceranger count now quantifies fluorescence intensity in the image at every barcoded-spot location.

Space Ranger 1.3.1 (Nov 1, 2021)

  • tar.gz compression

    Download for Linux 64-bit (tar.gz)
    File size: 1.2 GB
    md5sum: c2eb73125d9ee731fa825ea3734be1b4
    curl -o spaceranger-1.3.1.tar.gz "https://cf.10xgenomics.com/releases/spatial-exp/spaceranger-1.3.1.tar.gz?Expires=1770480758&Key-Pair-Id=APKAI7S6A5RYOXBWRPDA&Signature=AWi9Pbf46azw4uB7bmb05JmScHMxPqZgKzBASqo3KUIkCKB3rj9n9e1BEX7MUtakwyjEbc0GXjBvlevCChW0oNCIEqBlXussxj7Bwun1MRRHmRzQc6fON6fGb6MJ9oLdw86f8BIlnSWlef10QgXqOq2ciTvVQHoWv0JNAph3ELcimOPkASmzcjwFRHeZLOEEG6qBUkEMUlLOUflRJGODTMWZidvnnTQ1Mvn~jQDobFjEiF7qFaJh9BM9kd1pf8pAWVRFXYy8I0h6o-H2z7fNe1dFKXx5azhGYxL~V3JX2CUS1DhiH8r4twqLhuACehVrHoyiCgiUwXqQ05AiGF-AQg__"

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Space Ranger 1.3.1 highlights

  • Adds an alert if image alignment would have produced a different result if the --reorient-images option was specified.
  • Update warning for low fraction of reads confidently mapped to the probe set to be more informative.
  • Unsets additional sysconfig environment variables prior to pipeline execution, which may otherwise interfere with the pipeline conda environment.
  • Fixes an issue with mkfastq when bcl2fastq requires LD_LIBRARY_PATH.

Space Ranger 1.3.0 (Jun 9, 2021)

  • tar.gz compression

    Download for Linux 64-bit (tar.gz)
    File size: 1.2 GB
    md5sum: ede7f98db5adf7785e35ae0508c48f74
    curl -o spaceranger-1.3.0.tar.gz "https://cf.10xgenomics.com/releases/spatial-exp/spaceranger-1.3.0.tar.gz?Expires=1770480758&Key-Pair-Id=APKAI7S6A5RYOXBWRPDA&Signature=lG2j2idBsp8hJ1drsw8VMy8KCpZi5o-d8wNxP-fUeEvlcnmOwj3JpIMD10PZvRH6mjO0YmQSNn5EYdqJnLnKhIDmQ~DNtkOb7xv7fBdeMEJEU4EZf5fJtKRpleQp-dq2lZSWaws42Ne3ETzHTSDXZz9mjXrPdZDJh5z6yA~XhJuvk9SreKQab--tGi8-AKXvnOusuZOLPrp0KDfQIvfZwIW4YR8yvzpI09noFFCyxzLCBDZuewG2~RqT-eWqGPqTzvm03m0BPN4MEImpJ5y6RyMJF977heEU8afXun9TBrheCglaylNEYO-ahh6Z~WhSgbadbnYrBa6beTVI1liJcA__"

Download is unavailable on mobile devices.

Space Ranger 1.3.0 highlights

  • The recommended operating systems for Space Ranger 1.3.0 are CentOS 7 or Ubuntu 14 Linux variants or newer. CentOS 6 and Ubuntu 12 are still supported but have been deprecated.
  • Gene Expression analysis from formalin fixed paraffin embedded (FFPE) samples is now available in Space Ranger and is invoked by specifying the --probe-set option when running the spaceranger count command. Space Ranger 1.3.0 or later is required to analyze FFPE data.
  • Space Ranger now calculates the Moran's I spatial autocorrelation metric on a per-gene basis.

Space Ranger 1.2.2 (Feb 3, 2021)

  • tar.gz compression

    Download for Linux 64-bit (tar.gz)
    File size: 1.2 GB
    md5sum: 3280a085714ce7c894dc14b76312bcda
    curl -o spaceranger-1.2.2.tar.gz "https://cf.10xgenomics.com/releases/spatial-exp/spaceranger-1.2.2.tar.gz?Expires=1770480758&Key-Pair-Id=APKAI7S6A5RYOXBWRPDA&Signature=dNzZOxlUZBu6vRACf8dbuFZ-~72eYwyUiBrc3~fCjVZLBQKNe~0SJOatFvvGCi-amYS6s3cSMXUx3M6T9cULejZcbh2o~uhwdo4abuAtPqb0a6-vDDX41PIKDVd5fv6Tcu~P~XzoBdvsEJjM76LMcBdO3s6I80wj5Jle2bHMWQvZrchznrl670SfI~OvJPbjzJKKsPuAABZ01ZWYCxk5zA5LDIS4xHYVI9JHNkL7IbJwi845MhoNZBgk72GKjaQA5xu6hTqTQUvamBlV7YQwD1u-qhZBGAuBQlMJyeG~DsM5131WdcFI9OATKyergXTbGVgnum~PKtKDPRAIJwVL1A__"

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Space Ranger 1.2.2 highlights

  • Adds support for pyramid TIFFs, or TIFFs with multiple pages of the same image at different resolutions.
  • Fixes an issue where targeted samples run against new references would fail preflight.

Space Ranger 1.2.1 (Dec 10, 2020)

  • tar.gz compression

    Download for Linux 64-bit (tar.gz)
    File size: 1.2 GB
    md5sum: c24ecfc95c5e4f1c268354c5934da98e
    curl -o spaceranger-1.2.1.tar.gz "https://cf.10xgenomics.com/releases/spatial-exp/spaceranger-1.2.1.tar.gz?Expires=1770480758&Key-Pair-Id=APKAI7S6A5RYOXBWRPDA&Signature=E3umyjL11pwnOZeEjORwxAa2S-tP8qnUUnLY2CfyvFlejpkRjqQPiD3GIqZF2fUNo675gEMRGUw46vzFhIwSc7XI4Ywsy42QCoKAPOByzu0rF1ZFddwB4oPNXOQxxsHb~TjB50FIsX1m1Pb7R2FyN1yRgrW0LrHMhyfkIWRDVEwJFb5Wc3an2906xHzchmnSxEiwa6O8rXnPr0AILklUrtNbhHouE8EFLH9xFGWaaMuUL0hcVOufBUeAoik2KwaHCPUHekCbUB~tltyKwm~8ly4Cfrkv1It7itTBJuoY~qV6Jaeg1zf7ud4xal7DkK~NcqTl8Sv2miGC-8lrkumFPw__"

Download is unavailable on mobile devices.

Space Ranger 1.2.1 highlights

  • Fixed an issue in aggr where files would fail to be copied on NFSv4 File Systems.
  • Disables multithreading in mkref to address an issue where mkref would fail on hardware without AVX support.
  • Better error handling if the pipeline fails due to a missing .env.json file due to an incomplete copy of the application folder.

Space Ranger 1.2.0 (Oct 27, 2020)

  • tar.gz compression

    Download for Linux 64-bit (tar.gz)
    File size: 1.2 GB
    md5sum: fc21902700779111afc3c813bbb0ff5e
    curl -o spaceranger-1.2.0.tar.gz "https://cf.10xgenomics.com/releases/spatial-exp/spaceranger-1.2.0.tar.gz?Expires=1770480758&Key-Pair-Id=APKAI7S6A5RYOXBWRPDA&Signature=ASEJGfdjManpixULkuSQ9KOePnL3bnZwGHylA6j8wJ8rPzqSDCUx-v2kjwqVkXBVoc1u6Am7lXrIVckeK49MD0HX7TMiYPUZiLP8K4ZA~b-gx5deafT8fTBqICprCHg8Qdnr~Br8c1vtu-VqE-10lKQ-PPPm7TCA~lyzKY4d~YSBgb7fAFf2Nl4-PuR2TYjbBYZvDnB~mEGcuEYUSN80kncBem6YvJBJU5eNvEvPEDuj-eWJQo3vgetznuk48IdjIdwuA5YSOu0eGqhe1z97v9scIxY120kIvxcZjWF-vmVkBx1hBE4V70e4~LTrtAtoFrnqXu~s9R~2Ewt6XhePpg__"

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Space Ranger 1.2.0 highlights

  • Targeted Gene Expression analysis is available in Space Ranger 1.2.
  • Introduces the new spaceranger targeted-compare pipeline for direct comparative analysis of matched parent Whole Transcriptome Amplification (WTA) and Targeted Gene Expression datasets.
  • Includes the spaceranger targeted-depth subcommand to estimate sequencing depths appropriate for Spatial Targeted Gene Expression experiments.
  • A new command line option, --no-bam, instructs the pipeline not to construct BAM files.

Space Ranger 1.1.0 (Jun 23, 2020)

  • tar.gz compression

    Download for Linux 64-bit (tar.gz)
    File size: 1.2 GB
    md5sum: 708b93997295db31bc457b3d9af79ca2
    curl -o spaceranger-1.1.0.tar.gz "https://cf.10xgenomics.com/releases/spatial-exp/spaceranger-1.1.0.tar.gz?Expires=1770480758&Key-Pair-Id=APKAI7S6A5RYOXBWRPDA&Signature=AUdfEblgqiQyimbfA5exW4G-ome009wjVgOMROjNUf~S4f6ms7grZZVEB~hsDmZzwJObjawZviAkzZy-CXsVLm9FH1vOGHxPC2HfY3HBXHt7uLa~qhhFOJcc~YHuuoKSBk8IyL-n~NHGOrzQ5eWGFJ9-TeabUTl7B05aNDDyC0vFg9sXe557zg--qecETCYWXxcQD4PRJpW95BBEN0KM7mRJcY2ooJZn~8UN37Gn1Djxw862zrJlGYJqGYbUqvXDe51U977u5FfslVYhdiwf1C0rWgp2eVbKhBLIX-F1r0EgOrxTpuhoplH20SNZWcvcTDUOpKmxDUrjIAxlVlN3SA__"

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Space Ranger 1.1.0 highlights

  • Support for fluorescence imaging input such as IHC/IF.
  • Aggregation of multiple datasets.
  • Optional automatic rotation of slide images.

Space Ranger 1.0.0 (Dec 2, 2019)

  • tar.gz compression

    Download for Linux 64-bit (tar.gz)
    File size: 1.3 GB
    md5sum: 5cc7fb86d0cbff7df687b11575efb7cb
    curl -o spaceranger-1.0.0.tar.gz "https://cf.10xgenomics.com/releases/spatial-exp/spaceranger-1.0.0.tar.gz?Expires=1770480758&Key-Pair-Id=APKAI7S6A5RYOXBWRPDA&Signature=Uul~b9EoNJhJ7EIfacCPzQzkEJWF19b0I95okSui7PlNKdYU81QTeBVmf7rLffNpAmyxqLEZQeQTgJ6CzP5JPAciNR7IXuQl4yDu8fvttB1RCFDKeJTs3gc5TTdlJ~-PMTduf969L-j4B12nat7srEsnmJiXrYgF2rVOXvSPhmMLHFL53QeL7o4G5Lp06pxxPf7fqESlXIzmFTz89TpL5eqbRqPwWDgw8F3KCXDVgoZ-zeKkYc0GR9EYx1nUaKB6Rbjl87tm~wnotJdLcFf-4fx-yM1Cn7tpRvOE9tgn4xqV0a10ECehVMrBrIGucfFG5mZz5bBMvEgHt13Zs68zDw__"

Download is unavailable on mobile devices.

Space Ranger 1.0.0 highlights

  • Initial release of Space Ranger.