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Previous Versions

Previous Versions

Space Ranger 4.0.1 (Jun 12, 2025)

  • tar.gz compression

    Download for Linux 64-bit (tar.gz)
    File size: 885 MB
    md5sum: b0beb100947717cee8c7ad0d7a9f0247
    curl -o spaceranger-4.0.1.tar.gz "https://cf.10xgenomics.com/releases/spatial-exp/spaceranger-4.0.1.tar.gz?Expires=1774659456&Key-Pair-Id=APKAI7S6A5RYOXBWRPDA&Signature=HmdmxquRkKrIT5AKJsB3y7vB5e~q-vubsWsLjZ-IbbtjRn0TAc-qh8S8JaIF~cgnPRKqUhJoRVbRtnFbiRTPZvmhbl~OC1hxWZxZnSyqn2fyOhwjznGgXMhrfQXmqON1vJD5~uozneIoKw7hvpzD~-TmXI5KmpzJGsKiBtr8lvS~yfN9TBZtmnRMPUE92oFc-HXOhNuLc1UyfFA9sMkPlZx62s46qS4Jbat0f0mkbIjd57lbX~RsL6fd7XHJtdwu~buSMgny36doFP~STxOzDAwzUaORpERHJrLX-PckE0oSH3ylgpiMFZCg9ttLhTJIvMjR04702FbnVMbiLPT2oA__"
  • tar.xz compression

    Download for Linux 64-bit (tar.xz)
    File size: 582 MB
    md5sum: 3610ff948a6f8129cf49509f1bb34970
    curl -o spaceranger-4.0.1.tar.xz "https://cf.10xgenomics.com/releases/spatial-exp/spaceranger-4.0.1.tar.xz?Expires=1774659456&Key-Pair-Id=APKAI7S6A5RYOXBWRPDA&Signature=PoD2He5M2dxWbHdB5cQL8uOLC~XSDn~f3X5U8WDqG3Td2C3XRIwxtyubvQ1k79D29AAorcceRpUmYl2VvPQIkNbD~vPVRSAXT2Wip9EecoLpcQ6qfYIJRG8~9R8lInkrVVyGQZd0Mk4~PKCVggclDmu0w7WbKScYybl45a3utC~U7sI2QKSXF8R7TID7LsbWTwRERicwvDqcE5hIXpd4rzCF9wBKydP8D-a8xHEHDK-o9Zaxk8e21HU-haAIMBbRQTFz5Ahcg5Y6AAT7BHoxuO7MoWVqof0q-4a~zrLyg-lAdA5ihsJouSREbj0YYPRXcz7Uy1aRTOejpoqxwedwqQ__"

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Space Ranger v4.0.1 highlights

  • Space Ranger v4.0 now supports Visium HD 3' Gene Expression!
  • Cell and nucleus segmentation are now included for Visium HD and Visium HD 3' data with H&E images.
  • Space Ranger v4.0 now features a new UMI-based registration algorithm for Visium HD and Visium HD 3' data.
  • Starting with v4.0, anonymized telemetry data is collected and sent to 10x Genomics.
Release notes

Space Ranger 3.1.3 (Feb 6, 2025)

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    Download for Linux 64-bit (tar.gz)
    File size: 829 MB
    md5sum: 2cc7128cd538108d2a8a737ec54df484
    curl -o spaceranger-3.1.3.tar.gz "https://cf.10xgenomics.com/releases/spatial-exp/spaceranger-3.1.3.tar.gz?Expires=1774659456&Key-Pair-Id=APKAI7S6A5RYOXBWRPDA&Signature=S1~4S8HgtIYu4ChYs~7RWvg144n8nzX8XeKQbmS1wyzEf6BC8Sqlvx-N6UMea0GNtWffL2NR9RlzYg0VZE7vXZ5zVLmIWxeEYG70~tob2I99S-KrOtLwC7URzJls-iB-dvPkVRhoPT79XjYk~OfQhdj8SRM74oJzbU57q1JvTVEVsfeUBLaJLoPDcXQ8cdQfhPly2sMxJ0DLt8yUtKqVIQWjlZfrGJhpxt7aX4NpBN7NHFfRdMotaRW1dzmFv2Bmz-ZBH9xGz~MBA-2cCLfz0QmXeA0AOJS-FLxvJKXI6d355G4RLXSnYwqf~lziF1dHW5G~dXuZ2JbaWLu1Fka~3g__"
  • tar.xz compression

    Download for Linux 64-bit (tar.xz)
    File size: 529 MB
    md5sum: 2756aa7e3b66139059667117546c41bb
    curl -o spaceranger-3.1.3.tar.xz "https://cf.10xgenomics.com/releases/spatial-exp/spaceranger-3.1.3.tar.xz?Expires=1774659456&Key-Pair-Id=APKAI7S6A5RYOXBWRPDA&Signature=conuR9wewr5HHdNi3ZvWOZl8dBII1HNgdnMIlqhrMk6S~cu-1Cdrqb-7CdgX~aTM4QzV4iKfmM-J~~tdhwyqKdwO3FwiXAYoWXxBQCnkRutcxIXDHT24myIsUiWwgtQKCde0rI~rjOTWkNReAWphnM~PrUeJ-osxRsUsP4WKb4a7MTzJCoYNJxRRtPED7nNV3y8v2DWjQt10mEYs73NFd~NTQ1uuPDMu4kjTtL369WwrG3mxDcfjuS4Yqyiu9vJGPjMRK2JkW5PcWxWQfAc-wb15hefahMXn7LHNOobaE9pyEdZ15DqOKJy5cVDX4SCUG8A56dr5zPVAtA3ohiyDeA__"

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Space Ranger v3.1.3 highlights

  • Restored support for AVX1 machines.
  • Other miscellaneous bug fixes.

Space Ranger 3.1.2 (Nov 18, 2024)

  • tar.gz compression

    Download for Linux 64-bit (tar.gz)
    File size: 867 MB
    md5sum: 949088b1e2cc5bd03079b60a65b41d39
    curl -o spaceranger-3.1.2.tar.gz "https://cf.10xgenomics.com/releases/spatial-exp/spaceranger-3.1.2.tar.gz?Expires=1774659456&Key-Pair-Id=APKAI7S6A5RYOXBWRPDA&Signature=fD0cf24S6S9PkSIN-vIhfTvaP4ZMT00O5BN~7dL1GFZHOFeALDwrnPS63DLQg826j5L-vschmj2qocxNHQBrpMbiT2sSftEGXkYqFgFWF-yTP8vLK8R3IU8NWNXGYvm4yqEZvwlwrjuHlgtOaS8PKXLrF7wufSC5HTL9L3oqWlTGnxRU4pW1smd6O4TU1FiQ7MFHzcoVrJBhVYPFgj8cyuZceKQCWBstrZOTvgBdlnNo9nZQVNd7FJk6W8K8p3wfWH~sUh3QAupKk873npmFaKlTFDNTbHdavvuuvNo~EqjpNomao87Mk-RH4w1~OBueoM9~qtw40DLiaIWBC7y-AQ__"
  • tar.xz compression

    Download for Linux 64-bit (tar.xz)
    File size: 552 MB
    md5sum: 5a923ae250eea2974fd1cef7b2f9c1e2
    curl -o spaceranger-3.1.2.tar.xz "https://cf.10xgenomics.com/releases/spatial-exp/spaceranger-3.1.2.tar.xz?Expires=1774659456&Key-Pair-Id=APKAI7S6A5RYOXBWRPDA&Signature=Tdmos4cKp1MrZBu1dOGxWD8JVvTH8z5EnUbIo8Z21mlG8gWdDkI72QqOwZVB3UfrWBpQ2n4FXZ0FW1yRITHoRHDE6JIChARdDcaW9L4oepaBAYUTzOx58ZVwcmi9qZyP1GJhpowMl9CeEWJd2uwv0XAZO8LfNB09sLOVGiVm6DRQp-7rfI6Xsc0Y83IGa36gaFJYPICSEXI9EAhF8jZ74HMzN1qprEdZBS3M1YBoxbcQCTDd6TgxpjMMHsJQx5oct~5WpA2xG3XIAQ2zc92WmnDR1aXDRS1SFdnNgewyzgQw8ULN-wlqSX3mC5cpfYRySNM1pPP4p1~BsE1YxADJCw__"

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Space Ranger v3.1.2 highlights

  • In Space Ranger v3.1.2, the pipeline automatically corrects Visium HD CytAssist images generated with instrument firmware v2.1 to account for a bug that affects registration between gene expression data and the microscope image.
  • Adds metrics “Number of UMIs per mm squared of Tissue” and “Number of Reads per mm squared of Tissue” to the web_summary.html file.

Space Ranger 3.1.0 (Aug 28, 2024)

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    Download for Linux 64-bit (tar.gz)
    File size: 827 MB
    md5sum: 13a2c82adfb1f1efb737e2be121000d1
    curl -o spaceranger-3.1.0.tar.gz "https://cf.10xgenomics.com/releases/spatial-exp/spaceranger-3.1.0.tar.gz?Expires=1774659456&Key-Pair-Id=APKAI7S6A5RYOXBWRPDA&Signature=MWHwTILNU3Lgue8lcDqCuUdKNcsAIbekosAmIGGscpPbVsG2Q8mQWtKNs6I0VcUlXb9crO4atEBHN2VWdWXjVBkDZzvwMGBUEN5g5BLQ5wqEmOe3vxlzcN5ZFaJhi8mj3ROUvcvn3Ya7zFyOU9QL1UhWT0WdPnei3lkBBrhLQkXCH2gAdkBicvV~atdt2lCJMHyPHGkwSTrWh6Jzlw9PBm2SzsYtl5QaFo4fXV1tDfLNPzjULRLlFIncf4SoM3VnkssARQ~3xU6nHIyjtYdyw4iVK0I2geOf2gV2sCjeq6tg~sI3eygTE~ZnCLcD8Zg7yTBl0~XE8YjS5nvTNzcvqg__"
  • tar.xz compression

    Download for Linux 64-bit (tar.xz)
    File size: 527 MB
    md5sum: 28010d3724e9effc488470a961fe39fd
    curl -o spaceranger-3.1.0.tar.xz "https://cf.10xgenomics.com/releases/spatial-exp/spaceranger-3.1.0.tar.xz?Expires=1774659456&Key-Pair-Id=APKAI7S6A5RYOXBWRPDA&Signature=Svom4votMO3vreN2s5Jb6lMMqbh4-xN5~uJ-vs0qAbz7N0i8olZQLCnEIb-l8DFhi35ChLLVJbrURazKNTZ7aqLQEiqeAJ~3P7xMX5oVnAMmpvdxNRmAjFUGESC4-E1EPaP0ESHivWl4~zA1TZpW5sai4VsrMTv58kw5ptHsxXGnsaemnTMxzB5fX8jgYxrpBvt4bPj49ECzfcioPqsH9JGoovef5oB-NQmKiV3uBMxfWGXTjJnzednzl5Fk5cUaQUyrVxSof7kD2rn20BrEKGWBw7j9m8vvkQEsUMCDq5R5aFl6VuOCBoJMg37U0bs4QwrulPipvLMU0n82nAyEaQ__"

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Space Ranger 3.1.0 highlights

  • In Space Ranger v3.1.0, the pipeline has been overhauled to significantly improve the CytAssist to microscope image registration process.

Space Ranger 3.0.1 (May 31, 2024)

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    Download for Linux 64-bit (tar.gz)
    File size: 757 MB
    md5sum: ae65e7ffdddbb966277b7d1776f8c63c
    curl -o spaceranger-3.0.1.tar.gz "https://cf.10xgenomics.com/releases/spatial-exp/spaceranger-3.0.1.tar.gz?Expires=1774659456&Key-Pair-Id=APKAI7S6A5RYOXBWRPDA&Signature=SOe9BBok-Zfd13t6beFNu7-VTu0gevcDsXFAoZIS7nmj1c8mDUAlesUQDjs4HCSaenGTLxQulLEx~jqMyyGyJSG83vbWjSoJiMsEEtnFwIn3NohhdMtSrnex86QHo3TW5tJonhl~UpYBLz~18WwfLXVAn77XLd9dJF3Q-iK6K4Fq4y3wbQyxNoj4xfKw7wPap-jYcOzKBHnRfLV909XMx66xVHDgez0MMjJTdcqVqqPcT8zaH7Yjbd1B6yAk7XV7b2IlxLSj1oQJrzBa5YUS2H497nbiHEJMWJ840TRu~HFuyuHE0S~l5ZI~ugN4TJsDRWZUb4R9SWAhTCfbxOQmNw__"
  • tar.xz compression

    Download for Linux 64-bit (tar.xz)
    File size: 481 MB
    md5sum: 451495ee2074ff9adbac49ff8851ea1b
    curl -o spaceranger-3.0.1.tar.xz "https://cf.10xgenomics.com/releases/spatial-exp/spaceranger-3.0.1.tar.xz?Expires=1774659456&Key-Pair-Id=APKAI7S6A5RYOXBWRPDA&Signature=F-6l5oqgqZfcDttkAMFNIAxke5mLaRySrF0HrNsF7IGjXDM66A8ybyqLZwNpR9-KqHR45c-qpT2Nsmx2MwYNz8gYi2yNtTPl~pAOaAslDsTI22pjzSMfGvvdV5v45gC1dAaVZTRKVOsmdFSa~8E48qGA-AhfrYC1nBO7bPaqF8efMZKBMDugeJR--G1ze4zj9bxe56twxKHcheoYhO3H3QV0O656Q09Wa7~I1t-ASKU7HvqpD4KzRFKM0O0hB31Yio4e4ob2r7qdup3oTWNXkyNKiAFBl2xVZfX9r0wCYpLx-E0XSRZlYoEUMbv~DbO3y-46gnzu3RtmVlUFsiJTHw__"

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Space Ranger 3.0.1 highlights

  • Space Ranger v3.0 now supports Visium HD!
  • Space Ranger v3.0.1 includes bug fixes and other improvements.

Space Ranger 3.0.0 (Mar 25, 2024)

  • tar.gz compression

    Download for Linux 64-bit (tar.gz)
    File size: 795 MB
    md5sum: 19f4443f10cf94aff5768bd8968cb214
    curl -o spaceranger-3.0.0.tar.gz "https://cf.10xgenomics.com/releases/spatial-exp/spaceranger-3.0.0.tar.gz?Expires=1774659456&Key-Pair-Id=APKAI7S6A5RYOXBWRPDA&Signature=GXPua8LGYXVQG~Q1Mkvw472-e3BKiOo8Kj3ox02cGdxwBA2TLrW8rjVTpEZAC5Aw927SHZ73sTHXFYExGYE3eD3OJ3wCNJVbBsUevm9DAcbBgpt5r1l8370j4qSBxBjcJRL4nqOpIP8yPAhyedgkYfg6fO9756c756pwKHbmy3uuY3u5CMJic0Leu03cRRQp6q19wQd6mohMvCs9naTzd3o15qKaTDNhXvY24M9~r1KGc6ZwD7FltalENW2Q-O~wDFDZSAfLYADWXmAjDBGVg41ob~ZXlfLA8ecVV-ePGZ65dGqWgVLu3u-yEXh3Hfsj71A74G-QBVnTdBF8rJ7LAg__"
  • tar.xz compression

    Download for Linux 64-bit (tar.xz)
    File size: 507 MB
    md5sum: cd02b83fe849672066c40a1734819432
    curl -o spaceranger-3.0.0.tar.xz "https://cf.10xgenomics.com/releases/spatial-exp/spaceranger-3.0.0.tar.xz?Expires=1774659456&Key-Pair-Id=APKAI7S6A5RYOXBWRPDA&Signature=OHpPQaOOjABs8Qntehml3wmiu7ZEt1YHXMVNGOtKBvDhgnFbHTCx8auySjpkws3BQYyAw4E8vd9qvWp18s2NBNUVtI7F0w~lVKwk7YQuZpOI5agBLxs0SqSdaMgrxVtWYoi2sPYTdBBtNk6xR~8xbJ06J7AuubKWmicmulAsIPpvL8tv8tVPJtNGJFzRYJK12Pu4pP5NG95x0DRxbmkKAohAT7KVx5GsHE4ih8r4Y4C8wk3LUewZ1wu5cnNuVQR1fKcHRoBTa1nIf-3k3OA28TWU-OnIqe4V529GmPcCI8iLoKpETA-9c7AzeMdiM554-KCa7l9OnaXZbwGYIAoLfA__"

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Space Ranger 3.0.0 highlights

  • Space Ranger now supports Visium HD!

Space Ranger 2.1.1 (Oct 2, 2023)

  • tar.gz compression

    Download for Linux 64-bit (tar.gz)
    File size: 707 MB
    md5sum: 0ef64524af2735bd2a0fc9eef5a605f6
    curl -o spaceranger-2.1.1.tar.gz "https://cf.10xgenomics.com/releases/spatial-exp/spaceranger-2.1.1.tar.gz?Expires=1774659456&Key-Pair-Id=APKAI7S6A5RYOXBWRPDA&Signature=FEgtSzl6wing6xrmHoX69N-he7xx2oADsaLNfW8ILiEmBewxwNONxgVkyyJDIMoqVyStTPZbENHPehsThi445mtdRGENHI65OTSqS1-tQ61plNHU5pQFMdWFye5GYxESx8xm~3ZoekzaPExixZbMyByIlIM4shdyjvnRYPE-G6~OOOZPxEwtFqhMgODsYrj5wr5PtG3qPOdAQYRaEvnqTWTU313A6C8oI3bVRgU2asiPj8Kl10shwp93BQK9nXeqVLmbKih2r9bJ4oblEuBNMq3MmDXlGtUup3AjuBlBTy4YkIankg2gGQFqukQ6r-bIqUwuwN1dw0UX9fjtXvONHg__"
  • tar.xz compression

    Download for Linux 64-bit (tar.xz)
    File size: 465 MB
    md5sum: e1204bb11b3589bc5d5af244b51bfc18
    curl -o spaceranger-2.1.1.tar.xz "https://cf.10xgenomics.com/releases/spatial-exp/spaceranger-2.1.1.tar.xz?Expires=1774659456&Key-Pair-Id=APKAI7S6A5RYOXBWRPDA&Signature=OdxP-ytKMMOts2dY3lqqGRjujRTSuw7BhfI2~jAIfTcV5vXFtRAMfHmizzLr~rmd3mzrWDlvhy1GxJmpl4qWl-hkSYcpZrTdATzrDCfaY1Ke-dHIM3gVE7lv8Y0Fv8vYXcumlE3U5ZdYpUCfX-YYy2EJfo~x34y5MK4qRb14w1xzyThmehkSyYkHpuJsPHA7l-YES8labbZmFtjMMAPf0s1EjaWQymkIfZYpWdWVBSFsasxl9TeJJkleKqANWv45N23f9PTOsc2e37~tB-8j4O5ZstyBayPr09A8qkiTZ~Qfto-PhWiwYk35KQu7AhC8yiKM51B6NviA0h9NJD3Vuw__"

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Space Ranger 2.1.1 highlights

  • Fixed a bug where 8-bit grayscale images were inadvertently turned into 8-bit RGB color images for tissue registration.

Space Ranger 2.1.0 (May 16, 2023)

  • tar.gz compression

    Download for Linux 64-bit (tar.gz)
    File size: 707 MB
    md5sum: ee94c453c44770b2b69d6be46b948e3e
    curl -o spaceranger-2.1.0.tar.gz "https://cf.10xgenomics.com/releases/spatial-exp/spaceranger-2.1.0.tar.gz?Expires=1774659456&Key-Pair-Id=APKAI7S6A5RYOXBWRPDA&Signature=chR6D1jx58Mw-PDAt-oSfrGlms5pbq528zisq-QIkOdO6quapJoNDtIHxoIew-BDjH~EPknVGsGFtXw4cdXRkjuOz9pBbf7CCU2ONffsCMmzn~-b2PDQhSdRAfZ4V5cdZnzOeCpX4y5qYX9hWXE3KfPsSoXDtkpbtjaI-hixv2kNhdeARYv6xV6-EZ9y-j500swcrzBFX-l68Qj2oh0fLeB58qkhXIvBxGUI8x2VZX4vRovZfArn2yZPmguc~wjKpZ4LuOkBfyVYVv6ANoopjOldRBbN6opYWfahn3P7S-mFXSyKw3~Lr207eg9Htvj~yEEQD6W4I-Vd2tJEHb6rTw__"
  • tar.xz compression

    Download for Linux 64-bit (tar.xz)
    File size: 465 MB
    md5sum: a0d90129a81c41cbdd728e23a4d25161
    curl -o spaceranger-2.1.0.tar.xz "https://cf.10xgenomics.com/releases/spatial-exp/spaceranger-2.1.0.tar.xz?Expires=1774659456&Key-Pair-Id=APKAI7S6A5RYOXBWRPDA&Signature=GQbzwimJW5VK0bAy0d7fFARjbejKDLQ20Vl2gk~SRs~BC-C7gCn6CXnIkGcq24e86Lqb2inTB9U2Qkrk~IFFMXdmCGkCjSoOMIsbftFDQ23jn~tcQxgprYZazsfDUiSN46RMDFmn9Pz~p8t5q~DbrxrRuBlQsn7tgfUhIY8Ipsh36Lhd80MZ8dfZ0IpRYuE-IAMwm3LJ77j3lukoqvt3DMCUPN0SciNpIvr-KrQ5Pikbz-6YQLOqeqZ8272s7O2XoeRcqsnkRw7T-KH0clZgyzSnL0jU4HyPqYwjOh-LsVVsm-XkV28W6Y7bT~66fS00j24p~UxfZB9aSTv3nyO-Xw__"

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Space Ranger 2.1.0 highlights

  • New feature: Gene + Protein Expression on Visium CytAssist.
  • New feature: Reference-free spot deconvolution.
  • Added support for bigtiff (btf, tf2, and tf8) image file extensions.

Space Ranger 2.0.1 (Dec 7, 2022)

  • tar.gz compression

    Download for Linux 64-bit (tar.gz)
    File size: 664 MB
    md5sum: 26151804338ae4d4b44151232bd64b50
    curl -o spaceranger-2.0.1.tar.gz "https://cf.10xgenomics.com/releases/spatial-exp/spaceranger-2.0.1.tar.gz?Expires=1774659456&Key-Pair-Id=APKAI7S6A5RYOXBWRPDA&Signature=mWDyfGOY6rItLTdcCUjgweXc0ddzLHow0EbfMcu2t-JSaKvHXhawhr3F37BLK27NyQZ-Y2WEYE1vkV0VLwJ4iuPFwEVCZe7NZ-fuwKCoT-FBvm79poUMhIPbGqYfx78tAEy16PAT1XxgYEN6vNkyOZNgmPebV1SoIA~iEO2LmLDuTYc724eNVGRfJCFB9recdgEjFg40UqYhBu-ZzuZJkZV~hWAuxrPnHVdl9AzQQaOuKD0WVc4-je~4zWkpcdDIoF1COZQ5qiL642ajwrlhFBqIfEi5L~3laz9MjcrrxGhrEQtIzwPKbnD0TOVXLsTneyNXZqANbpknzR6hElo1oA__"

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Space Ranger 2.0.1 highlights

  • Reclustering workflow now supports generating a UMAP projection in addition to the t-SNE projection.
  • Visium Image Manual Aligner now includes additional support for images with difficult to detect fiducials.
  • A new Spatial Enrichment table which allows users to sort and filter features by their Moran’s I value for Visium Spatial Gene Expression is added.

Space Ranger 2.0.0 (Jul 18, 2022)

  • tar.gz compression

    Download for Linux 64-bit (tar.gz)
    File size: 662 MB
    md5sum: aec9ec128c7bc9fbf9fd6d31aa390d4c
    curl -o spaceranger-2.0.0.tar.gz "https://cf.10xgenomics.com/releases/spatial-exp/spaceranger-2.0.0.tar.gz?Expires=1774659456&Key-Pair-Id=APKAI7S6A5RYOXBWRPDA&Signature=l--Gx-F3ZAfOcAof6AwRruJPHoZNS9a7E1va-58RttUBHgM82fwJk~hvPCLWBBVYoCIU~oYA~O68HJi2k2n5jM0ziWlUAAkqzdr5tqOuLkDJzQE6afOQK7tuaPNERYvupxdKmJnpqhl-JvsKAZTRCAHY96mXnUWKufLbWll8dKUP1lMzw~L5HwYa-h-OtMyqDH0W9DmtoCefACLgLgPOQT65NRRyybfoyVvzH3l7KmhTF0O3ehD-fZEAsZCy781zzlcBHbG9htc3Wt-PUl5veKJRxtHWARj6ibes7x3ZppuR2lgjLzdovCOIyAShUnHBvhkdMA1PHbY-mEZiEunFLQ__"

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Space Ranger 2.0.0 highlights

  • Space Ranger now supports CytAssist-enabled Gene Expression analysis and includes image registration between the CytAssist image and the microscope image of the same tissue section.
  • spaceranger count now quantifies fluorescence intensity in the image at every barcoded-spot location.

Space Ranger 1.3.1 (Nov 1, 2021)

  • tar.gz compression

    Download for Linux 64-bit (tar.gz)
    File size: 1.2 GB
    md5sum: c2eb73125d9ee731fa825ea3734be1b4
    curl -o spaceranger-1.3.1.tar.gz "https://cf.10xgenomics.com/releases/spatial-exp/spaceranger-1.3.1.tar.gz?Expires=1774659456&Key-Pair-Id=APKAI7S6A5RYOXBWRPDA&Signature=dlo4fkInmdH2h~pO3FFLYzNbYYCV5G2wKb4wSa7Z6Dx1l9vfsEp7VxX~sJn8UdEIMp4HUQjKuaZJDg43u~wVk7jjjE9MVBZpuIaQkl~acIftTYyIeIBQdS5IAZOthYBP2~zCClDnyOUs7Y2IIE58OdLypII61UCOaqIoAn-9msFWt4wVchvkkSSoB330e38PGWufRHpDrk2WgEkyC4RCK1tX7SpDjyghQAKbBkjL2ixH8CdYtsIrdh7xqipQoJBX-swScRbYz9Uxv1azvnVA86nD6MJKxqF5p9vHfD9P2YxOKStJRDM6JrSIgZ6ib7auImbhWftqWb3C~RsNeBwwcQ__"

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Space Ranger 1.3.1 highlights

  • Adds an alert if image alignment would have produced a different result if the --reorient-images option was specified.
  • Update warning for low fraction of reads confidently mapped to the probe set to be more informative.
  • Unsets additional sysconfig environment variables prior to pipeline execution, which may otherwise interfere with the pipeline conda environment.
  • Fixes an issue with mkfastq when bcl2fastq requires LD_LIBRARY_PATH.

Space Ranger 1.3.0 (Jun 9, 2021)

  • tar.gz compression

    Download for Linux 64-bit (tar.gz)
    File size: 1.2 GB
    md5sum: ede7f98db5adf7785e35ae0508c48f74
    curl -o spaceranger-1.3.0.tar.gz "https://cf.10xgenomics.com/releases/spatial-exp/spaceranger-1.3.0.tar.gz?Expires=1774659456&Key-Pair-Id=APKAI7S6A5RYOXBWRPDA&Signature=NrgEwCu~Y9srZ5TE80uhSMqfGEsGZ~zD-D2H2oRmQkJx9hq5S4zHMdmKHXQyR~LUL3SpsEz3OBA7naPLMYRZ3qeu~jJC-PMteWzfg-pKqBU4bEZFyEi1ZpY33eBes0zqgdeLn6b~h1hDr7-wwu5HMeyFAAYK6yEsGJi-wQqc24-H7t01XjvdI0uQiibhEVyY~WOkLRiSnvxN04WwE5q6ezSccQh1ZwxeqUKFH443Uuj32yg7EFySEiDLSRPu2-LFuM4GHYva~k1sReoq5LauIqnpwceCNYyFAgX6cGBewgnmyTJoDVc2qoGynQJ1u0goXxzhn0pSYJlA0EiA9VeyzA__"

Download is unavailable on mobile devices.

Space Ranger 1.3.0 highlights

  • The recommended operating systems for Space Ranger 1.3.0 are CentOS 7 or Ubuntu 14 Linux variants or newer. CentOS 6 and Ubuntu 12 are still supported but have been deprecated.
  • Gene Expression analysis from formalin fixed paraffin embedded (FFPE) samples is now available in Space Ranger and is invoked by specifying the --probe-set option when running the spaceranger count command. Space Ranger 1.3.0 or later is required to analyze FFPE data.
  • Space Ranger now calculates the Moran's I spatial autocorrelation metric on a per-gene basis.

Space Ranger 1.2.2 (Feb 3, 2021)

  • tar.gz compression

    Download for Linux 64-bit (tar.gz)
    File size: 1.2 GB
    md5sum: 3280a085714ce7c894dc14b76312bcda
    curl -o spaceranger-1.2.2.tar.gz "https://cf.10xgenomics.com/releases/spatial-exp/spaceranger-1.2.2.tar.gz?Expires=1774659456&Key-Pair-Id=APKAI7S6A5RYOXBWRPDA&Signature=O3Ue4RcK-aGyRlrNhArOvbIGx4ly8FFDfYuQi8fWTu~3out2sjl2AKDMQx5DeaTgTaQQofy1PiCo68ZUjCgE0Skp-0eJ~VuFbf2vgKPyklp59e0gNrKdSoLZMvGyA8-VrASY0F-w6pCiicU7VKZ~DIWfYLC6~tCBye0DcAfUMhUybIXRwiq~eRB50ZYnCyRYZU7ZfXs~20GFUL2Y5JlZusq3P-geBH1wx9hfzjn3OqlJcDdvkw8BZJGIbpo185BWfx2oDSr0aL30QWM3BfRSX60ZvjSMhl2wDRjcAIv6Kv6np7ZwhzKbOnymkTxHz2PpTDXjrbaPC17fWVWL5kDfkQ__"

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Space Ranger 1.2.2 highlights

  • Adds support for pyramid TIFFs, or TIFFs with multiple pages of the same image at different resolutions.
  • Fixes an issue where targeted samples run against new references would fail preflight.

Space Ranger 1.2.1 (Dec 10, 2020)

  • tar.gz compression

    Download for Linux 64-bit (tar.gz)
    File size: 1.2 GB
    md5sum: c24ecfc95c5e4f1c268354c5934da98e
    curl -o spaceranger-1.2.1.tar.gz "https://cf.10xgenomics.com/releases/spatial-exp/spaceranger-1.2.1.tar.gz?Expires=1774659456&Key-Pair-Id=APKAI7S6A5RYOXBWRPDA&Signature=G3zQOXzy8ZzfoEbAI10VzPNmayagRhFvsJig8iAm8ii1WoFhyCMkrQcsEwU59AHQxsRzzOi7-yG8GbflHeemQ4Xvx7RKPTuhqi8IDL~Hw1u0SHhCOPezLwZ6XGCHXK~Fl-0kZIGl~PIF7fZkPFnFKPXefdoREzUp43kiSP4oxF5k9SOdWLZ67TyuvC3uAS9mwFHBurTOCNGYLIhQn8y9VvefUfAFfSEIrQvKEuetT4TGz7rBtgNRzO4oeqcEt3dui8-8CEMeZLWlvYUfP6bfS9xpf4haZCLpDAs2D0y0APv7TDuDVtjKmk35cwX7Sr0RGdlssIIXoHkrbuTg7in2vg__"

Download is unavailable on mobile devices.

Space Ranger 1.2.1 highlights

  • Fixed an issue in aggr where files would fail to be copied on NFSv4 File Systems.
  • Disables multithreading in mkref to address an issue where mkref would fail on hardware without AVX support.
  • Better error handling if the pipeline fails due to a missing .env.json file due to an incomplete copy of the application folder.

Space Ranger 1.2.0 (Oct 27, 2020)

  • tar.gz compression

    Download for Linux 64-bit (tar.gz)
    File size: 1.2 GB
    md5sum: fc21902700779111afc3c813bbb0ff5e
    curl -o spaceranger-1.2.0.tar.gz "https://cf.10xgenomics.com/releases/spatial-exp/spaceranger-1.2.0.tar.gz?Expires=1774659456&Key-Pair-Id=APKAI7S6A5RYOXBWRPDA&Signature=MPpzkAFKTK08stjYKhyiSeDjI7KUynXhL6gA71RVLRkR-GeKFgH9m1i9laVv-CZunSYXNgLe-vPscyTxQ-kFhGoLf-xJ3KOWR6IuxyfjHgrbvQEgFUYhiG4G2BejMQeCOSh1t7CJDQ-J92k9JfFWZ-0aZ6MIU0PRyS39d1pSjPfHkz9qVH66KqGVZC73pAJZEQBJfB7p4-2UVjfqj5djCJqL46YHq0Qc2wSSQPzmXJSDoUjnfQi43TZokwTsZQr6DSMWv7rYASKPYQkPhmPuT3GqK8hJ3QDoz-FLEllBO2Y6ANFUckSD-Ws8EITTH0yTCu4MiZ5u6ouoLAVFB3hX5w__"

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Space Ranger 1.2.0 highlights

  • Targeted Gene Expression analysis is available in Space Ranger 1.2.
  • Introduces the new spaceranger targeted-compare pipeline for direct comparative analysis of matched parent Whole Transcriptome Amplification (WTA) and Targeted Gene Expression datasets.
  • Includes the spaceranger targeted-depth subcommand to estimate sequencing depths appropriate for Spatial Targeted Gene Expression experiments.
  • A new command line option, --no-bam, instructs the pipeline not to construct BAM files.

Space Ranger 1.1.0 (Jun 23, 2020)

  • tar.gz compression

    Download for Linux 64-bit (tar.gz)
    File size: 1.2 GB
    md5sum: 708b93997295db31bc457b3d9af79ca2
    curl -o spaceranger-1.1.0.tar.gz "https://cf.10xgenomics.com/releases/spatial-exp/spaceranger-1.1.0.tar.gz?Expires=1774659456&Key-Pair-Id=APKAI7S6A5RYOXBWRPDA&Signature=lxb2xfvOESErCYEU5NlR0ZUZGvJc3qkgmsdnbAOnMDfnxirstIZNgQSI4GowUxbdN4MZL2esWcizNH~g6Mz9RG~oUbMGQnVx4llL4VJS5KNAO3E2GZ5hnJJW56vWN0VIvq5mLie21wdgnNyiLq~Nmdm1jaRvd~U9qTiKb2QoWgc5b14NFBSlcHydNAoMWa94UWVw1DtO1bzYIy5YC5FCWYbr452OuD2IeXtbgNdltPU82oxd4SQUmtFuMxpngQDCodLBINRPRTZs3MghjgN27ZMtvid5Xt1Hn7xERnQ7ztN9EjlVI46gn9i14lBC9I3GVu1H3YwgRqY3ZLi9FAiXGA__"

Download is unavailable on mobile devices.

Space Ranger 1.1.0 highlights

  • Support for fluorescence imaging input such as IHC/IF.
  • Aggregation of multiple datasets.
  • Optional automatic rotation of slide images.

Space Ranger 1.0.0 (Dec 2, 2019)

  • tar.gz compression

    Download for Linux 64-bit (tar.gz)
    File size: 1.3 GB
    md5sum: 5cc7fb86d0cbff7df687b11575efb7cb
    curl -o spaceranger-1.0.0.tar.gz "https://cf.10xgenomics.com/releases/spatial-exp/spaceranger-1.0.0.tar.gz?Expires=1774659456&Key-Pair-Id=APKAI7S6A5RYOXBWRPDA&Signature=ifchCBxKFahIEXNKkiqH-FCWAODMvnAbhc0xRenHbN8QHt7vM5VgCQoKdqrH~3EP3BeKb4B62PWxmcuOdne-Zp5SIImC1qVZhUMvdUQIhb7GRA34UxsiushdXNAsWKudzf0EAMw7IeARZ~Faup9EntXRX~Xyql33v32QWTGwZWfvflJicdkQy9I59JQYgIdkLWSqIKF1ReUY-vLA0Nemyo7tajsI5mfvj0Z~JeVa1pUJ7TnSI1Tw~4UcpfYqY545uMKt~p55zedJVyS9ohsDnE3UizmmOjtJM4mxqNAeWaIiwkqeJ3ldZAglXUAhkVpYpfWLG-f3yR9A7gce4mOyEg__"

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Space Ranger 1.0.0 highlights

  • Initial release of Space Ranger.